Tiny and Big is a 3D physics puzzler with comic-book like graphics (down to cross hatching on most objects) in which you play a fellow with a laser and a grappling hook, pursuing some gink who has stolen your grandfather's underpants. (Or in other words, the backstory is absurd and largely irrelevant, simply providing an arbitrary motivation.)
Most of the world (but not all) is destroyable and deformable; the puzzles mainly involve cutting up pieces of the environment and moving them around to gain access to the next area you may reach.
Since it's physics based, there are potentially multiple solutions to each problem, which is fine; the basic problem with the game, however, is that mouse control is muddy as hell, and even something as simply as moving along a ramp is tricky. Combined with the fine control sometimes necessary to build what you're trying to put together, this is a formula for frustration. I kept wishing that the options would allow me to use the system mouse pointer instead of theirs -- muddy mouse control usually results from insisting on painting the pointer in the game's canvas. And doubtless if I had a faster machine, it would be less of a problem, albeit I'm not exactly running on a low-end PC here.
Tiny and Big is in beta; among other things, the soundscape is extremely sparse. It's a 2011 IGF Student Showcase finalist.